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Test Code SQ C2CMPM, EPIC LAB5438 C2 Complement, Functional, with Reflex, Serum

Reporting Name

C2 Complement,Functional,w/Reflex,S

Useful For

The investigation of a patient with a low (absent) hemolytic complement (CH50)

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
C4 Complement C4, S Yes No
C3 Complement C3, S Yes No
C2AG C2 Complement, Antigen, S No No

Testing Algorithm

If the C2 result is <15 U/mL, then C3, C4, and C2AG will be performed at an additional charge.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum Red

Specimen Required

Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after drawing the specimen, place the tube on wet ice.

2. Spin down and separate serum from clot.

3. Immediately freeze specimen.

Additional Information: Fasting preferred.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen 21 days

Reference Values

25-47 U/mL

Day(s) and Time(s) Performed

Monday through Saturday; 3 p.m.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86161-C2 complement, functional

86160-Complement C3 (if appropriate)

86160-Complement C4 (if appropriate)

86160-C2 Complement Antigen (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C2 C2 Complement,Functional,w/Reflex,S 33408-6


Result ID Test Result Name Result LOINC Value
C2FX C2 Complement,Functional,S No LOINC Needed
INT53 Interpretation 69048-7

Reject Due To


Mild OK; Gross OK


Mild OK; Gross reject


Mild OK; Gross OK



Method Name

C2: Automated Liposome Lysis Assay

C2AG: Radial Immunodiffusion-Binding Site