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HelpTest Code SQ OPATUM, EPIC LAB5401 Opiates Confirmation, Urine
Reporting Name
Opiate Confirmation, UUseful For
Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine
Performing Laboratory
Mayo Medical Laboratories in Rochester
Specimen Type
UrineSpecimen Required
Container/Tube: Plastic, 60-mL urine bottle
Specimen Volume: 20 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Additional Information:
1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order OPATX / Opiates Confirmation, Chain of Custody, Urine.
2. If urine creatinine is required or adulteration of the sample is suspected, the following test should be requested, ADULT / Adulterants Survey, Urine. For additional information, refer to ADULT / Adulterants Survey, Urine.
3. Submitting <20 mL will compromise our ability to perform all necessary testing.
Specimen Minimum Volume
2.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 14 days |
Reference Values
Negative
Cutoff concentrations
Codeine by LC-MS/MS: 25 ng/mL
Dihydrocodeine-by LC-MS/MS: 25 ng/mL
Hydrocodone by LC-MS/MS: 25 ng/mL
Norhydrocodone-by LC-MS/MS: 25 ng/mL
Hydromorphone by LC-MS/MS: 25 ng/mL
Oxycodone by LC-MS/MS: 25 ng/mL
Noroxycodone-by LC-MS/MS: 25 ng/mL
Oxymorphone by LC-MS/MS: 25 ng/mL
Noroxymorphone-by LC-MS/MS: 25 ng/mL
Naloxone-by LC-MS/MS: 25 ng/mL
Morphine by LC-MS/MS: 25 ng/mL
Day(s) and Time(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80361
80365
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| OPATU | Opiate Confirmation, U | 74760-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 6543 | Codeine-by LC-MS/MS | 16197-6 |
| 42000 | Dihydrocodeine-by LC-MS/MS | 16211-5 |
| 21177 | Hydrocodone-by LC-MS/MS | 19483-7 |
| 42001 | Norhydrocodone-by LC-MS/MS | 61421-4 |
| 21179 | Hydromorphone-by LC-MS/MS | 18473-9 |
| 21178 | Oxycodone-by LC-MS/MS | 19643-6 |
| 42002 | Noroxycodone-by LC-MS/MS | 61424-8 |
| 35023 | Oxymorphone-by LC-MS/MS | 18325-1 |
| 42003 | Noroxymorphone-by LC-MS/MS | In Process |
| 42004 | Naloxone-by LC-MS/MS | In Process |
| 6542 | Morphine-by LC-MS/MS | 16196-8 |
| 21180 | Opiates Interpretation | 69050-3 |
Reject Due To
|
Hemolysis |
Mild OK; Gross OK |
|
Lipemia |
NA |
|
Icterus |
Mild OK; Gross OK |
|
Other |
NA |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Forms
1. Chain-of-Custody Request Form is included in the Chain-of-Custody Kit (T282). A copy of this form is also available at http://www.mayomedicallaboratories.com/it-mmfiles/chain-of-custody-request-form.pdf.
2. If not ordering electronically, complete, print, and send a General Request Form (T239) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf).