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Test Code SQ SICKLE, EPIC LAB339 Hemoglobin S, Screen, Blood


Hemoglobin S Solubility
Useful in detecting the presence of hemoglobin S.

Performing Laboratory

Meriter Laboratories

Specimen Requirements


Specimen Type: Whole blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 4 mL

Minimum Volume: 1 mL


Specimen Type: Whole blood

Container/Tube: Lavender top (EDTA) Microtainer

Specimen Volume: .5 mL

Minimum Volume: 100 µL


Alternative Container: Sodium Citrate or ACD

Specimen Transport Temperature



Reference Values

Negative (reported as positive or negative)

Precautions: This test does not distinguish heterozygous hemoglobin S trait from homozygous hemoglobin S disease, nor from any of the following conditions: S/C, S/D, S/G, S/E, S/thalassemia, S/O-Arab, and S/Georgetown trait.  A follow-up Hemoglobin Electrophoresis (SQ HGBELM, EPIC LAB2529) is recommended for all positive and/or questionable tests. 

Day(s) Test Set Up

Monday through Sunday

Analytical Time


1 hour


4 hours

Test Classification and CPT Coding



Refrigerated: 14 days