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Test Code SQ THEO, EPIC LAB35 Theophylline, Plasma

Methodology

Kinetic Interaction of Microparticles (KIMS)

Performing Laboratory

Meriter Laboratories

Specimen Requirements

Once a steady-state has been achieved, and when peak and trough values are not critical, a draw time of 3 to 8 hours is recommended after a coated capsule oral dose; 8 to 24 hours is recommended after a slow-release oral dose; 30 minutes to 6 hours is recommended after an intravenous dose; and, 3 to 8 hours is recommended after a suppository dose.

 

Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Plasma

Container/Tube: Light-green top (lithium heparin gel)

Specimen Volume: 1 mL

Collection Instructions: Avoid hemolysis and lipemia.

 

Alternate:

Specimen Type: Serum

Container/Tube: Red top

Specimen Volume: 1 mL

Collection Instructions: Avoid hemolysis and lipemia.

Specimen Transport Temperature

Refrigerated <48 hours/Frozen OK

Reference Values

Therapeutic concentration: 5.0-15.0 mcg/mL
Critical value (automatic call-back): ≥20 mcg/mL

Day(s) Test Set Up

Monday through Sunday

Analytical Time

Stat:

1 hour

Routine:

4 hours

Test Classification and CPT Coding

80198

Specimen Requirements Additional Information

Specimen Stability:

Plasma is stable refrigerated (2o C-8o C) for 7 days when capped and frozen (-20o C) for 60 days when capped.